Metabolic Regulation in Mammals

Rating:
Summary: Wrestling enzymes the old-fashioned way
Review: This book will do little to encourage people to renew their interest in metabolism - it has no point of comparison, for example, with Dan Atkinson's classic Cellular Energy Metabolism and its Regulation, which was packed with interesting and stimulating ideas on every page. It is "dedicated to those who wrestled enzymes from tissues the old-fashioned way", and that, alas, is just how it reads.

As a book on metabolism it is adequate. However, the title mentions regulation, and it falls far short of what one would hope for in a book on metabolic regulation. Depending on one's taste and background one would expect some treatment of cooperative and allosteric interactions, of feedback inhibition, of protein kinases and phosphatases, and of the newer view of metabolic regulation that is emerging from work in metabolic control analysis. Of the last of these there is nothing; the other topics do get mentioned, but the treatment is skimpy.